Annexin VII anticorps (AA 122-429)
Aperçu rapide pour Annexin VII anticorps (AA 122-429) (ABIN1885990)
Antigène
Voir toutes Annexin VII (ANXA7) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 122-429
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 122 and 429 of Human ANXA7
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Annexin VII (ANXA7) (Annexin A7 (ANXA7))
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Autre désignation
- Annexin VII
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Sujet
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Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA.An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain.The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle.The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals.Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids.The latter domain is composed of alternating hydrophobic and hydrophilic segments.Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.[provided by RefSeq]
Synonyms: ANX7 -
Poids moléculaire
- 53 kDa
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ID gène
- 310
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NCBI Accession
- NP_004025, NM_004034
Antigène
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